Update all your VST pugins to the latest versions and if it’s possible the Live software too since Windows 10 is used. If this won’t help, disable VST pugins one-by-one and try saving again on each disabling.

I’m using the same software version on Mac OSX 64 and to me jBridgeM ( for Mac OS X ) VST bridge works well. jBridgeM aims to make it possible to run 32bit bit VST plugins in 64 bit VST hosts and vice-versa. You can find instructions and try the demo on this website.